Family: CTX-M
Class: A
Number of Variants: 147
Number of Proteins: 229
Number of Structures: 5
Taxonomic Lineage: Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae
  Alignment     Variability Plot     Phylogenetic Tree     Mutational Profile     Fingerprint     Sequences  
Variants Organism Uniprot ID PDB ID Hydrolytic profile Embl ID Genbank ID
CTXM-1 Escherichia coli I7ABV7 NA NA JN676835 JN676835.1
Escherichia coli Q5MAG2 NA NA AY847143 AY847143.1
Klebsiella pneumoniae I7AC52 NA NA JX268711 JX268711.1
Klebsiella pneumoniae Q5MAG0 NA NA AY847145 AY847145.1
Klebsiella pneumoniae H6UQH3 NA NA JN676835 JN676835.1
Escherichia coli I6JM45 NA NA AKST01000509 AKST01000509.1
Escherichia coli H6UQI5 NA NA JN676847 JN676847.1
Escherichia coli P28585 NA Penicillins, first, second and third-generation Cephalosporins X92506 X92506.1
Escherichia coli I6YE46 NA cefotaxime and ciprofloxacin JX206414 JX206414.1
Escherichia coli I6ZI70 NA Penicillins, first, second and third-generation Cephalosporins JX206420 JX206420.1
Escherichia coli I6Z191 NA Penicillins, first, second and third-generation Cephalosporins CP003699CP003699.1
Escherichia coli I6YE63 NA Penicillins, first, second and third-generation Cephalosporins JX206419 JX206419.1
Escherichia coli I6ZM32 NA Penicillins, first, second and third-generation Cephalosporins JX206428 JX206428.1
Escherichia coli I6YPP4 NA Penicillins, first, second and third-generation Cephalosporins JX206437 JX206437
Escherichia coli I6ZI59 NA Penicillins, first, second and third-generation Cephalosporins JX206415JX206415.1
Escherichia coli I6ZM27 NA Penicillins, first, second and third-generation Cephalosporins JX206423 JX206423.1
Escherichia coli I6ZM40 NA Cefotaxime,Ciprofloxacin JX206438 JX206438.1
Escherichia coli I6Z9G4 NA Penicillins, first, second and third-generation Cephalosporins JX206416 JX206416.1
Escherichia coli I6YE73 NA Penicillins, first, second and third-generation Cephalosporins JX206429 JX206429.1
Escherichia coli I6YPK7 NA Penicillins, first, second and third-generation Cephalosporins JX206417 JX206417.1
Escherichia coli I6ZI96 NA Penicillins, first, second and third-generation Cephalosporins JX206440 JX206440.1
Escherichia coli I6YE83 NA Penicillins, first, second and third-generation Cephalosporins JX206439 JX206439.1
Escherichia coli I6ZI86 NA Penicillins, first, second and third-generation Cephalosporins CP003699 CP003699.1
Escherichia coli I6YPN5 NA Penicillins, first, second and third-generation Cephalosporins JX206427 JX206427.1
Escherichia coli I6Z9I0 NA Penicillins, first, second and third-generation Cephalosporins JX206426 JX206426.1
Escherichia coli I6ZM14 NA Penicillins, first, second and third-generation Cephalosporins JX206418 JX206418.1
Escherichia coli I6YE79 NA Penicillins, first, second and third-generation Cephalosporins JX206434 JX206434.1
Escherichia coli I6ZI82 NA Penicillins, first, second and third-generation Cephalosporins JX206425 JX206425.1
Escherichia coli I6YPN9 NA Penicillins, first, second and third-generation Cephalosporins JX206432 JX206432.1
Escherichia coli I6Z9J1 NA Penicillins, first, second and third-generation Cephalosporins JX206441 JX206441.1
Escherichia coli I6ZM37 NA Penicillins, first, second and third-generation Cephalosporins JX206433 JX206433.1
Escherichia coli I6Z9H7 NA Penicillins, first, second and third-generation Cephalosporins JX206421 JX206421.1
Escherichia coli I6YE68 NA Penicillins, first, second and third-generation Cephalosporins JX206424 JX206424.1
Escherichia coli I6Z9I8 NA Cefotaxime,Ciprofloxacin JX206436 JX206436.1
Escherichia coli I6Z9I3 NA Penicillins, first, second and third-generation Cephalosporins CP003699 CP003699.1
Escherichia coli I6YPM8 NA Penicillins, first, second and third-generation Cephalosporins JX206422 JX206422.1
Escherichia coli D1LFF1 NA Penicillins, first, second and third-generation Cephalosporins GQ983277 GQ983277.1
Klebsiella pneumoniae A8D3A8 NA Penicillins, first, second and third-generation Cephalosporins EU136031 EU136031.1
CTXM-2 Salmonella typhimurium P74841 NA Cefotaxime X92507 X92507
Klebsiella pneumoniae H6UQJ9 NA NA JN676861 JN676861.1
Klebsiella pneumoniae Q4LAV0 NA NA FJ815248 FJ815248.1
Salmonella infantis Q7AYD2 NA NA AJ311891 AJ311891.1
Vibrio cholerae Q1G696 NA NA DQ310703 DQ310703.1
Morganella morganii Q704F7 NA NA 41023646 AJ621187.1
CTXM-3 Enterobacter Cloacae Q6BBQ3 NA NA 324036051 HQ214052.1
Klebsiella pneumoniae Q7X573 NA NA GQ325711 GQ325711
Shigella flexneri 2a F1C693 NA NA HQ203199 HQ203199.1
Shigella sonnei F1C691 NA NA HQ203197 HQ203197
Shigella dysenteriae 2a F1C694 NA NA HQ203200 HQ203200.1
Enterobacter aerogenes Q6BBQ5 NA NA EF437434 EF437434
Escherichia coli Q6BBP7 NA Ceftazidime EU418914 EU418914.1
Escherichia coli A3RJI2 NA Ceftazidime EF418608 EF418608.1
Salmonella senftenberg Q6L716 NA NA AB168117 AB168117.1
Citrobacter diversus Q7DHI8 NA NA AB185835 AB185835.1
Serratia marcescens Q6BBQ0 NA NA AM003902 AM003902.1
Citrobacter freundii O52904 NA NA Y10278 Y10278.1
Enterobacter Cloacae A0ESH3 NA NA DQ478706 DQ478706.1
Escherichia coli A0ESF3 NA Ceftazidime DQ478690 DQ478690.1
CTXM-4 Salmonella typhimurium O33807 NA Cefotaxime Y14156 Y14156.1
CTXM-5 Salmonella typhimurium O65975 NA Cefotaxime AJ005044 AJ005044.1
Salmonella typhimurium O34177 NA Cefotaxime JX017306 JX017306.1
CTXM-6 Salmonella typhimurium O65976 NA Cefotaxime AJ005045 AJ005045
CTXM-8 Citrobacter amalonaticus Q9RMT4 NA Cefotaxime AF189721 AF189721.1
CTXM-9 Escherichia coli H6UQH9 NA Cefotaxime JN6768431 JN6768431.1
Escherichia coli H6UQK0 NA Cefotaxime JN676862 JN676862.1
Enterobacter Cloacae C7E9V5 NA Cefotaxime GQ258850 GQ258850
Escherichia coli Q9L5C8 NA Cefotaxime AJ416345 AJ416345.1
CTXM-10 Klebsiella pneumoniae Q66W71 NA NA AF255298 AF255298
CTXM-11 Klebsiella pneumoniae Q9K5K0 NA Cefotaxime AY005110 AY005110.1
CTXM-12 Klebsiella pneumoniae Q9F5U0 NA Cefotaxime AF305837 AF305837.1
Klebsiella pneumoniae Q6ZXB6 3ZNY Cefotaxime AJ704396 AJ704396.1
CTXM-13 Klebsiella pneumoniae Q9L5C6 NA Cefotaxime AF252623 AF252623.1
CTXM-14 Escherichia coli H6UQI0 NA Cefotaxime JX268676 JX268676.1
Escherichia coli Q9L5C7 1YLT Cefotaxime FJ405218 FJ405218.1
Escherichia coli H6UQK3 NA Cefotaxime JN676865 JN676865.1
Escherichia coli A0ESF4 NA Cefotaxime DQ478691 DQ478691.1
Escherichia coli A0ESG7 NA Cefotaxime DQ478701 DQ478701.1
Escherichia coli H6UQJ0 NA Cefotaxime JN676824 JN676824.1
Klebsiella oxytoca I7AKC7 NA Cefotaxime JX268680 JX268680.1
Klebsiella oxytoca D2D9A0 NA Cefotaxime FJ494913 FJ494913.1
CTXM-15 Escherichia coli H6UQJ0 NA NA JN676824 JN676824
Escherichia coli I6ZR77 NA NA JX268654 JX268654.1
Klebsiella pneumoniae G8FPN5 NA NA JN019844 JN019844.1
Klebsiella pneumoniae Q2PUH3 NA NA 575010706 JQ686199
Klebsiella pneumoniae I7AKI5 NA NA JX268709 JX268709
Escherichia coli I6ZFV8 NA NA JX268660 JX268660
Escherichia coli H6UQH2 NA NA JN676834 JN676834.1
Escherichia coli H6UQJ5 NA NA JN676857 JN676857.1
Escherichia coli H6UQI3 NA NA JN676845 JN676845.1
Klebsiella pneumoniae I7AK97 NA NA JX268655 JX268655
Escherichia coli H6UQJ6 NA NA JX268664 JX268664
Escherichia coli I6ZR68 NA NA JX268662 JX268662
Kluyvera citrophila E3PQJ9 NA NA FN813246 FN813246
Citrobacter freundii G8FPP9 NA NA JN019853 JN019853
Escherichia coli G8FPM5 NA NA JN019834 JN019834
Proteus mirabilis G8FPP6 NA NA JN019836 JN019836
Citrobacter diversus G8FPM9 NA NA JN019837 JN019837
Klebsiella oxytoca G8FPN4 NA NA JN019839 JN019839
Enterobacter aerogenes G8FPM7 NA NA JN019835 JN019835
Klebsiella oxytoca I6ZG55 NA NA JX268714 JX268714
Enterobacter agglomerans D6PYN9 NA NA GU990085 GU990085
Escherichia coli C5I509 NA NA FJ668755 FJ668755
Escherichia coli G9J624 NA NA JN811628 JN811628
Escherichia coli G9J625 NA NA JN811629 JN811629
Escherichia coli G9J631 NA NA JN811636 JN811636
Escherichia coli G9J626 NA NA JN811630 JN811630
Escherichia coli G9J634 NA NA JN811638 JN811638
Escherichia coli G9J633 NA NA JN811637 JN811637
Escherichia coli G9J625 NA NA 359292322 JN811629
Escherichia coli G9J627 NA NA JN811631 JN811631
Escherichia coli G9J629 NA NA JN811633 JN811633
Klebsiella pneumoniae Q7BGE9 NA NA GU211011 GU211011
Escherichia coli K9UTH3 NA NA KC107824 KC107824
CTXM-16 Shigella sp. 16 H2DLZ0 NA NA JN627489 JN627489
Escherichia coli Q939N4 1YLW Cefotaxime AY029068 AY029068
CTXM-17 Klebsiella pneumoniae Q939K2 NA NA AF454633 AF454633
CTXM-19 Klebsiella pneumoniae Q93F82 NA Ceftazidime AF458080 AF458080
CTXM-20 Proteus mirabilis Q936V5 NA NA AJ416344 AJ416344
CTXM-21 Escherichia coli Q937J1 NA NA AJ416346 AJ416346
CTXM-22 Escherichia coli H6UQI6 NA NA N676848 JN676848
Klebsiella pneumoniae H6UQH0 NA NA JN676832 JN676832
Klebsiella pneumoniae Q8RLK8 NA NA AY080894 AY080894
CTXM-23 Escherichia coli Q8RMW4 NA Ceftazidime AF488377 AF488377
CTXM-24 Citrobacter freundii O52904 NA NA DQ328958 DQ328958
Escherichia coli Q4LB53 NA Ceftazidime GQ449685 GQ449685
Klebsiella pneumoniae Q8GKX4 NA NA AY143430 AY143430
CTXM-25 Escherichia coli Q8KSA6 NA NA AF518567 AF518567
CTXM-26 Klebsiella pneumoniae Q8GD10 NA NA AY157676 AY157676
CTXM-27 Escherichia coli D2Z1S3 NA NA JX206413 JX206413
Escherichia coli Q840M4 1YLP NA GQ896552 GQ896552
CTXM-28 Escherichia coli Q845L5 NA NA JQ686200 JQ686200
CTXM-29 Escherichia coli Q83ZQ7 NA NA AY267213 AY267213
CTXM-30 Citrobacter freundii Q7X587 NA NA AY292654 AY292654
CTXM-31 Providencia Sp. Q7X210 NA NA AJ567481 AJ567481
CTXM-32 Escherichia coli Q842A4 NA Ceftazidime AJ557142 AJ557142.1
CTXM-33 Escherichia coli Q842S3 NA NA AY238472 AY238472.1
CTX-M-34 Escherichia coli Q6R3N1 NA NA AY515297 AY515297.1
CTX-M-35 Klebsiella oxytoca Q5KT51 NA NA AB176534 AB176534
Escherichia coli Q5KT52 NA NA AB176533 AB176533.1
Klebsiella pneumoniae Q5KT53 NA NA AB176532 AB176532.1
CTX-M-36 Escherichia coli Q75NB4 NA NA AB177384 AB177384.1
CTX-M-37 Enterobacter cloacae Q6DQV0 NA NA AY649755 AY649755.1
CTXM-38 Klebsiella pneumoniae I7AKC0 NA NA JX268712 JX268712.1
Escherichia coli I6ZRE8 NA NA JX268712 JX268712.1
Klebsiella pneumoniae H6UQK2 NA NA JN676864 JN676864
Klebsiella oxytoca I6ZR88 NA NA JX268677 JX268677.1
Klebsiella pneumoniae Q5PXN8 NA NA AY822595 AY822595.1
CTXM-39 Escherichia coli Q58G80 NA NA 61741615 AY954516
CTXM-40 Escherichia coli Q5XLZ5 NA NA AY750914 AY750914
CTXM-41 Proteus mirabilis Q4TZY8 NA NA DQ023162 DQ023162
CTXM-42 Escherichia coli Q4JNX3 NA Ceftazidime DQ061159 DQ061159
CTXM-43 Acinetobacter baumannii Q4F896 NA NA DQ102702 DQ102702
CTXM-51 Escherichia coli Q3HLW4 NA NA DQ211987 DQ211987
CTXM-52 Klebsiella pneumoniae Q30B66 NA NA DQ223685 DQ223685
CTXM-53 Salmonella enterica Q2XPY6 NA Ceftazidime DQ268764 DQ268764.1
CTXM-54 Klebsiella pneumoniae Q2PT38 NA Ceftazidime DQ303459 DQ303459
CTXM-55 Shigella sp.62 H2DLZ1 NA Ceftazidime JN627490 JN627490.1
Escherichia coli Q0GA57 NA Ceftazidime GQ456157 GQ456157
CTXM-56 Escherichia coli A3FFV8 NA Ceftazidime EF374097 EF374097
CTXM-57 Salmonella typhimurium Q0PL62 NA NA DQ810789 DQ810789
CTXM-58 Escherichia coli A2TK51 NA NA EF210159 EF210159
CTXM-59 Klebsiella pneumoniae Q206M3 NA NA FJ815278 FJ815278.1
CTXM-60 Salmonella typhimurium A1KQS3 NA NA AM411407 AM411407
CTXM-61 Salmonella typhimurium A2TLT3 NA NA EF219142 EF219142
CTXM-62 Klebsiella pneumoniae A9XG17 NA NA EF219134 EF219134
CTX-M-63 Klebsiella pneumoniae Q5DVW7 NA NA AB205197 AB205197
CTX-M-64 Shigella sonnei A5LH21 NA oxyimino-cephalosporins Ceftazidime Cefotaxime AB284167 AB284167
CTXM-65 Escherichia coli B8XLK0 NA Cefotaxime FJ405214 FJ405214.1
CTXM-66 Proteus mirabilis A5JUR0 NA NA EF576988 EF576988.1
CTX-M-67 Escherichia coli A8DS72 NA Imipenem EF581888 EF581888
CTX-M-68 Klebsiella pneumoniae A8IW71 NA NA EU177100 EU177100
CTX-M-69 Escherichia coli B0ZTA3 NA NA EU402393 EU402393
CTX-M-71 Klebsiella pneumoniae C8YUV9 NA NA FJ815436 FJ815436.1
Providencia stuartii S4WGH4 NA NA KC571256 KC571256
CTX-M-72 Klebsiella pneumoniae Q5MAF7 NA NA AY847148 AY847148.1
CTX-M-74 Enterobacter cloacae C5MRF5 NA NA GQ149243 GQ149243.1
CTXM-75 Providencia stuartii C5MRF6 NA NA GQ149244 GQ149244
CTXM-76 Klebsiella ascorbata B3LE88 NA NA AM982520 AM982520
CTXM-78 Kluyvera georgiana B3LE91 NA NA AM982522 AM982522.1
CTXM-79 Escherichia coli A3RLQ6 NA NA FJ169498 FJ169498
CTXM-80 Klebsiella pneumoniae A8W9A7 NA NA EU202673 EU202673.1
CTXM-81 Klebsiella pneumoniae A8D3A8 NA NA EU136031 EU136031.1
CTXM-82 Escherichia coli Q2XT31 NA NA DQ256091 DQ256091.1
Escherichia coli B2CR57 NA NA EU545409 EU545409.1
CTXM-83 Salmonella derby B6E9R7 NA NA FJ214366 FJ214366.1
CTXM-84 Salmonella derby B6E9R8 NA NA FJ214367 FJ214367.1
CTXM-85 Salmonella enterica B6E9R9 NA NA FJ214368 FJ214368
CTXM-86 Salmonella enterica B6E9S0 NA NA FJ214369 FJ214369.1
CTXM-87 Escherichia coli B2CR57 NA Cefotaxime EU545409 EU545409
CTXM-88 Salmonella infantis C3VMM9 NA NA FJ873739 FJ873739.1
CTXM-89 Proteus mirabilis C5IXH9 NA NA FJ971899 FJ971899.1
CTXM-90 Salmonella enterica C4P9N4 NA NA C4P9N4 C4P9N4
CTXM-91 Proteus mirabilis D0ES28 NA NA GQ870432 GQ870432.1
CTX-M-92 Escherichia coli D1MAH3 NA NA GU127598 GU127598
CTX-M-93 Escherichia coli G0XMH2 NA NA HQ166709 HQ166709
CTX-M-94 Escherichia coli D9IQH0 NA NA HM167760 HM167760
CTX-M-96 Klebsiella pneumoniae Q6ZXB6 NA NA AJ704396 AJ704396
CTXM-97 Escherichia coli E1ANH6 NA Ceftriaxone Ceftazidime HM776707 HM776707.1
CTXM-98 Escherichia coli E2IZP4 NA NA HQ637575 HQ637575.1
CTXM-99 Klebsiella pneumoniae E0AF02 NA NA HM803271 HM803271
CTX-M-100 Escherichia coli E7AXL5 NA NA FR682582 FR682582
CTX-M-101 Escherichia coli F1CLM9 NA NA HQ398214 HQ398214.1
CTX-M-102 Escherichia coli F1CLN0 NA NA HQ398215 HQ398215.1
CTX-M-103 Escherichia coli S6FS81 NA NA HG423149 HG423149.1
CTX-M-104 Escherichia coli D2KL97 NA NA GU226840 GU226840.1
CTXM-105 Escherichia coli F1DG66 NA NA HQ833651 HQ833651.1
CTX-M-106 Escherichia coli F1DTB3 NA NA HQ913565 HQ913565.1
CTX-M-107 Shigella sp. G3EPW0 NA NA JF274244 JF274244.1
CTX-M-108 Shigella sp. G3EPW1 NA NA JF274245 JF274245.1
CTX-M-109 Shigella sp. G3EPW4 NA NA JF274248 JF274248
CTX-M-110 Shigella sp. G3EPV8 NA NA JF274242 JF274242.1
CTX-M-111 Shigella sp. G3EPV9 NA NA JF274243 JF274243.1
CTX-M-112 Shigella sp. G3EPW2 NA NA 343480072 JF274246
CTX-M-113 Shigella sp G3EPW3 NA NA JF274247 JF274247.1
CTX-M-114 Providencia rettgeri C7FE03 NA NA GQ351346 GQ351346.1
CTX-M-116 Proteus mirabilis F8UXB4 NA NA JF966749 JF966749.1
CTX-M-117 Proteus mirabilis G9FYZ9 NA NA JN227085 JN227085.1
CTXM-121 Escherichia coli H6V561 NA NA KF021999 KF021999.1
CTX-M-122 Escherichia coli H6V562 NA NA JN790863 JN790863.1
CTXM-123 Escherichia coli H6V563 NA NA KC160505 KC160505.1
CTXM-124 Escherichia coli I0DEV3 NA NA JQ429324 JQ429324.1
CTXM-125 Enterobacter cloacae M1F7E6 NA NA JQ724542 JQ724542.1
CTXM-126 Escherichia coli H7CHS5 NA NA 380035724 AB703103
CTX-M-129 Escherichia coli R4I5F7 NA NA JX017364 JX017364.1
CTXM-130 Escherichia coli R4I5F6 NA NA JX017365 JX017365.1
CTXM-131 Providencia rettgeri G9JVK3 NA NA JN969893 JN969893.1
CTX-M-132 Escherichia coli J7KCB4 NA NA JX313020 JX313020
CTX-M-134 Escherichia coli K7WEV5 NA NA JX896165 JX896165.1
CTX-M-136 Proteus mirabilis M1QVD4 NA NA KC351754 KC351754.1
CTX-M-137 Escherichia coli W0T351 NA NA AB900900 AB900900.1
CTX-M-138 Escherichia coli V5MYM2 NA NA KF526119 KF526119
CTX-M-141 Klebsiella pneumoniae R9S6T8 NA NA KC964871 KC964871.1
CTX-M-142 Escherichia coli U3N3M8 NA NA KF240809 KF240809.1
CTX-M-143 Salmonella typhi W0G2A6 NA NA KF019726 KF019726.1
CTX-M-147 Klebsiella pneumoniae V5N077 NA NA KF513180 KF513180.1
References
  • Gazouli M, Tzelepi E, Markogiannakis A, Legakis NJ, Tzouvelekis LS. Two novel plasmid-mediated cefotaxime-hydrolyzing beta-lactamases (CTX-M-5 and CTX-M-6)from Salmonella typhimurium. FEMS Microbiol Lett. 1998 Aug 15;165(2):289-93.PubMed PMID: 9742701
  • Gazouli M, Tzelepi E, Sidorenko SV, Tzouvelekis LS. Sequence of the gene encoding a plasmid-mediated cefotaxime-hydrolyzing class A beta-lactamase(CTX-M-4): involvement of serine 237 in cephalosporin hydrolysis. Antimicrob Agents Chemother. 1998 May;42(5):1259-62. PubMed PMID: 9593162
  • Gazouli M, Legakis NJ, Tzouvelekis LS. Effect of substitution of Asn forArg-276 in the cefotaxime-hydrolyzing class A beta-lactamase CTX-M-4. FEMSMicrobiol Lett. 1998 Dec 15;169(2):289-93. PubMed PMID: 9868772
  • Karfunkel D, Carmeli Y, Chmelnitsky I, Kotlovsky T, Navon-Venezia S. Theemergence and dissemination of CTX-M-producing Escherichia coli sequence type 131 causing community-onset bacteremia in Israel. Eur J Clin Microbiol Infect Dis.2013 Apr;32(4):513-21. doi: 10.1007/s10096-012-1765-9. Epub 2012 Nov 2. PubMedPMID: 23117265
  • Soge OO, Queenan AM, Ojo KK, Adeniyi BA, Roberts MC. CTX-M-15extended-spectrum(beta)-lactamase from Nigerian Klebsiella pneumoniae. JAntimicrob Chemother. 2006Jan;57(1):24-30. Epub 2005 Nov 30. PubMed PMID:16319181
  • Poirel L, Naas T, Le Thomas I, Karim A, Bingen E, Nordmann P. CTX-M-typeextended-spectrum beta-lactamase that hydrolyzes ceftazidime through a singleamino acid substitution in the omega loop. Antimicrob Agents Chemother. 2001Dec;45(12):3355-61. PubMed PMID: 11709308
  • Munday CJ, Boyd DA, Brenwald N, Miller M, Andrews JM, Wise R, Mulvey MR,Hawkey PM. Molecular and kinetic comparison of the novel extended-spectrumbeta-lactamases CTX-M-25 and CTX-M-26. Antimicrob Agents Chemother. 2004Dec;48(12):4829-34. PubMed PMID: 15561863
  • Liu W, Chen L, Li H, Duan H, Zhang Y, Liang X, Li X, Zou M, Xu L, Hawkey PM.Novel CTX-M {beta}-lactamase genotype distribution and spread into multiplespecies of Enterobacteriaceae in Changsha, Southern China. J AntimicrobChemother. 2009 May;63(5):895-900. doi: 10.1093/jac/dkp068. Epub 2009 Mar 18.PubMed PMID: 19297379
  • Kariuki S, Corkill JE, Revathi G, Musoke R, Hart CA. Molecularcharacterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found inclinical Klebsiella pneumoniae isolates from Kenya. Antimicrob Agents Chemother. 2001 Jul;45(7):2141-3. PubMed PMID: 11408239
  • Bonnet R, Recule C, Baraduc R, Chanal C, Sirot D, De Champs C, Sirot J. Effectof D240G substitution in a novel ESBL CTX-M-27. J Antimicrob Chemother. 2003Jul;52(1):29-35. Epub 2003 May 29. PubMed PMID: 12775683
  • Chen Y, Delmas J, Sirot J, Shoichet B, Bonnet R. Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobilityand decreased stability. J MolBiol. 2005 Apr 29;348(2):349-62. PubMed PMID:15811373
  • Zong Z, Partridge SR, Thomas L, Iredell JR. Dominance of blaCTX-M within anAustralian extended-spectrum beta-lactamase gene pool. Antimicrob AgentsChemother. 2008 Nov;52(11):4198-202. doi: 10.1128/AAC.00107-08. Epub 2008 Aug 25.PubMed PMID: 18725449
  • Lee SG, Jeong SH, Lee H, Kim CK, Lee Y, Koh E, Chong Y, Lee K. Spread ofCTX-M-type extended-spectrum beta-lactamases among bloodstream isolates ofEscherichia coli and Klebsiella pneumoniae from a Korean hospital. DiagnMicrobiol Infect Dis. 2009 Jan;63(1):7680. doi:10.1016/j.diagmicrobio.2008.09.002. PubMed PMID: 19073302
  • Chanawong A, M'Zali FH, Heritage J, Xiong JH, Hawkey PM. Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People'sRepublic of China. Antimicrob Agents Chemother. 2002 Mar;46(3):630-7. PubMedPMID: 11850241
  • Chen Y, Shoichet B, Bonnet R. Structure, function, and inhibition along thereaction coordinate of CTX-M beta-lactamases. J Am Chem Soc. 2005 Apr20;127(15):5423-34. PubMed PMID: 15826180; PubMed Central PMCID: PMC1360657
  • Bae IK, Lee YN, Lee WG, Lee SH, Jeong SH. Novel complex class 1 integronbearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 gene. Antimicrob Agents Chemother. 2007 Aug;51(8):3017-9. Epub 2007 May 21.PubMed PMID: 17517851
  • Navarro F, Mesa RJ, Miró E, Gómez L, Mirelis B, Coll P. Evidence forconvergent evolution of CTX-M-14 ESBL in Escherichia coli and its prevalence.FEMS Microbiol Lett. 2007 Aug;273(1):120-3. Epub 2007 Jun 7. PubMed PMID:17559406
  • Chen L, Hu H, Chavda KD, Zhao S, Liu R, Liang H, Zhang W, Wang X, Jacobs MR,Bonomo RA, Kreiswirth BN. Complete Sequence of a KPC-Producing IncNMultidrug-Resistant Plasmid from an Epidemic Escherichia coli Sequence Type 131Strain in China. Antimicrob Agents Chemother. 2014 Apr;58(4):2422-5. doi:10.1128/AAC.02587-13. Epub 2014 Jan 6. PubMed PMID: 24395232
  • Ho PL, Chan J, Lo WU, Lai EL, Cheung YY, Lau TC, Chow KH. Prevalence andmolecular pidemiology of plasmid-mediated fosfomycin resistance genes amongblood and urinary Escherichia coli isolates. J Med Microbiol. 2013 Nov;62(Pt11):1707-13. doi: 10.1099/jmm.0.062653-0. Epub 2013 Aug 29. PubMed PMID:23988630
  • Lee SY, Park YJ, Yu JK, Jung S, Kim Y, Jeong SH, Arakawa Y. Prevalence ofacquired fosfomycin resistance among extended-spectrum ß-lactamase-producingEscherichia coli and Klebsiella pneumoniae clinical isolates in Korea andIS26-composite transposon surrounding fosA3. J Antimicrob Chemother. 2012Dec;67(12):2843-7. doi: 10.1093/jac/dks319. Epub 2012 Aug 14. PubMed PMID:22893681
  • Literacka E, Bedenic B, Baraniak A, Fiett J, Tonkic M, Jajic-Bencic I,Gniadkowski M. blaCTX-M genes in escherichia coli strains from Croatian Hospitalsare located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. Antimicrob Agents Chemother. 2009 Apr;53(4):1630-5. doi:10.1128/AAC.01431-08. Epub 2009 Feb 2. PubMed PMID: 19188377
  • Sun Y, Zeng Z, Chen S, Ma J, He L, Liu Y, Deng Y, Lei T, Zhao J, Liu JH. High prevalence of bla(CTX-M) extended-spectrum ß-lactamase genes in Escherichia coli isolates from pets and emergence of CTX-M-64 in China. Clin Microbiol Infect.2010 Sep;16(9):1475-81. PubMedPMID: 21681998
  • Kiratisin P, Apisarnthanarak A, Saifon P, Laesripa C, Kitphati R, Mundy LM.The emergence of a novel ceftazidime-resistant CTX-M extended-spectrumbeta-lactamase, CTX-M-55, in both community-onset and hospital-acquired infections in Thailand. Diagn Microbiol Infect Dis. 2007 Jul;58(3):349-55. Epub2007 Apr 20. PubMed PMID: 17449211
  • Ma J, Liu JH, Lv L, Zong Z, Sun Y, Zheng H, Chen Z, Zeng ZL. Characterization of extended-spectrum ß-lactamase genes found among Escherichia coli isolates from duck and environmental samples obtained on a duck farm. Appl Environ Microbiol.2012 May;78(10):3668-73. doi: 10.1128/AEM.07507-11. Epub 2012 Mar 9. PubMed PMID:22407683
  • Sabaté M, Tarragó R, Navarro F, Miró E, Vergés C, Barbé J, Prats G. Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase(CTX-M-9)from Escherichia coli in Spain. Antimicrob Agents Chemother. 2000Jul;44(7):1970-3.PubMed PMID: 10858363
  • Tian SF, Chen BY, Chu YZ, Wang S. Prevalence of rectal carriage ofextended-spectrum beta-lactamase-producing Escherichia coli among elderly people in community settings in China. Can J Microbiol. 2008 Sep;54(9):781-5. doi:10.1139/w08-059. PubMed PMID: 18772941
  • Tian GB, Wang HN, Zou LK, Tang JN, Zhao YW, Ye MY, Tang JY, Zhang Y, Zhang AY,Yang X, Xu CW, Fu YJ. Detection of CTX-M-15, CTX-M-22, and SHV-2extended-spectrum beta-lactamases (ESBLs) in Escherichia coli fecal-sampleisolates from pig farms in China. Foodborne Pathog Dis. 2009 Apr;6(3):297-304.doi: 10.1089/fpd.2008.0164. PubMed PMID: 19272004
  • Pallecchi L, Bartoloni A, Fiorelli C, Mantella A, Di Maggio T, Gamboa H,Gotuzzo E, Kronvall G, Paradisi F, Rossolini GM. Rapid dissemination anddiversity of CTX-M extended-spectrum beta-lactamase genes in commensalEscherichia coli isolates from healthy children from low-resource settings inLatin America. Antimicrob Agents Chemother. 2007 Aug;51(8):2720-5.Epub 2007 Jun 4. PubMed PMID: 17548490
  • Deng Y, He L, Chen S, Zheng H, Zeng Z, Liu Y, Sun Y, Ma J, Chen Z, Liu JH.F33:A-:B- and F2:A-:B- plasmids mediate dissemination of rmtB-blaCTX-M-9 groupgenes and rmtB-qepA in Enterobacteriaceae isolates from pets in China. Antimicrob Agents Chemother. 2011 Oct;55(10):4926-9. doi: 10.1128/AAC.00133-11. Epub 2011Jul 25. PubMed PMID: 21788459
  • Zheng H, Zeng Z, Chen S, Liu Y, Yao Q, Deng Y, Chen X, Lv L, Zhuo C, Chen Z,Liu JH. Prevalence and characterisation of CTX-M ß-lactamases amongst Escherichiacoli isolates from healthy food animals in China. Int J Antimicrob Agents. 2012Apr;39(4):305-10. doi: 10.1016/j.ijantimicag.2011.12.001. Epub 2012 Feb 9. PubMed PMID: 22325120
  • Doi Y, Adams-Haduch JM, Paterson DL. Escherichia coli isolate coproducing 16S RNA Methylase and CTX-M-type extended-spectrum beta-lactamase isolated from anoutpatient in the United States. Antimicrob Agents Chemother. 2008Mar;52(3):1204-5. doi: 10.1128/AAC.01320-07. Epub 2008 Jan 14. PubMed PMID:18195064
  • Leinberger DM, Grimm V, Rubtsova M, Weile J, Schröppel K, Wichelhaus TA,Knabbe C, Schmid RD, Bachmann TT. Integrated detection ofextended-spectrum-beta-lactam resistance by DNA microarray-based genotyping ofTEM, SHV, and CTX-M genes. J Clin Microbiol. 2010 Feb;48(2):460-71. doi:10.1128/JCM.00765-09. Epub 2009 Dec 9. PubMed PMID: 20007393
  • Ahmed AM, Nakano H, Shimamoto T. The first characterization ofextended-spectrum beta-lactamase-producing Salmonella in Japan. J Antimicrob Chemother. 2004 Jul;54(1):283-4. Epub 2004 Jun 9. PubMed PMID: 15190029
  • Cui S, Li J, Sun Z, Hu C, Jin S, Li F, Guo Y, Ran L, Ma Y. Characterization of Salmonella enterica isolates from infants and toddlers in Wuhan, China. J Antimicrob Chemother. 2009 Jan;63(1):87-94. doi: 10.1093/jac/dkn452. Epub 2008 Nov 4. PubMed PMID: 18984647
  • Zhang W, Luo Y, Li J, Lin L, Ma Y, Hu C, Jin S, Ran L, Cui S. Widedissemination of multidrug-resistant Shigella isolates in China. J AntimicrobChemother. 2011 Nov;66(11):252735. doi: 10.1093/jac/dkr341. Epub 2011 Aug 22.PubMed PMID: 21859815
  • Abdalhamid B, Pitout JD, Moland ES, Hanson ND. Community-onset disease caused by Citrobacter freundii producing a novel CTX-M beta-lactamase, CTX-M-30, in Canada. Antimicrob Agents Chemother. 2004 Nov;48(11):4435-7. PubMed PMID:15504875
  • Minarini LA, Poirel L, Trevisani NA, Darini AL, Nordmann P. Predominance of CTX-M-type extended-spectrum beta-lactamase genes among enterobacterial isolates from outpatients in Brazil. Diagn Microbiol Infect Dis. 2009 Oct;65(2):202-6.doi: 10.1016/j.diagmicrobio.2009.05.021. PubMed PMID: 19748435
  • Vervoort J, Baraniak A, Gazin M, Sabirova J, Lammens C, Kazma M, Grabowska A, Izdebski R, Carmeli Y, Kumar-Singh S, Gniadkowski M, Goossens H, Malhotra-KumarS; MOSAR WP2; SATURN WP1 study groups. Characterization of two new CTX-M-25-group extended-spectrum ß-lactamase variants identified in Escherichia coli isolates from Israel. PLoS One. 2012;7(9):e46329. doi: 10.1371/journal.pone.0046329. Epub 2012 Sep 26. PubMed PMID: 23050014
  • Cartelle M, del Mar Tomas M, Molina F, Moure R, Villanueva R, Bou G.High-level resistance to ceftazidime conferred by a novel enzyme, CTX-M-32,derived from CTX-M-1 through a single Asp240-Gly substitution. Antimicrob Agents Chemother. 2004 Jun;48(6):2308-13. PubMed PMID: 15155242
  • Oteo J, Delgado-Iribarren A, Vega D, Bautista V, Rodríguez MC, Velasco M,Saavedra JM, Pérez-Vázquez M, García-Cobos S, Martínez-Martínez L, Campos J.Emergence of imipenem resistance in clinical Escherichia coli during therapy. IntJ Antimicrob Agents. 2008 Dec;32(6):534-7. doi:10.1016/j.ijantimicag.2008.06.012. Epub 2008 Sep 4. PubMed PMID: 18775649
  • Yuan L, Liu JH, Hu GZ, Pan YS, Liu ZM, Mo J, Wei YJ. Molecular characterization of extended-spectrum beta-lactamase-producing Escherichia coliisolates from chickens in Henan Province, China. J Med Microbiol. 2009 Nov;58(Pt 11):1449-53. doi: 10.1099/jmm.0.012229-0. Epub 2009 Jul 2. PubMed PMID: 19574412
  • Hopkins KL, Deheer-Graham A, Threlfall EJ, Batchelor MJ, Liebana E. Novelplasmid-mediated CTX-M-8 subgroup extended-spectrum beta-lactamase (CTX-M-40)isolated in the UK. Int J Antimicrob Agents. 2006 Jun;27(6):572-5. Epub 2006 May 12. PubMed PMID: 16697557
  • Djamdjian L, Naas T, Tandé D, Cuzon G, Hanrotel-Saliou C, Nordmann P.CTX-M-93, a CTXM variant lacking penicillin hydrolytic activity. AntimicrobAgents Chemother. 2011May;55(5):1861-6. doi: 10.1128/AAC.01656-10. Epub 2011 Feb22. PubMed PMID:21343457
  • Saladin M, Cao VT, Lambert T, Donay JL, Herrmann JL, Ould-Hocine Z, Verdet C, Delisle F, Philippon A, Arlet G. Diversity of CTX-M beta-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals. FEMS Microbiol Lett. 2002 Apr 9;209(2):161-8. PubMed PMID: 12007800
  • Chmelnitsky I, Carmeli Y, Leavitt A, Schwaber MJ, Navon-Venezia S. CTX-M-2 anda new CTX-M-39 enzyme are the major extended-spectrum beta-lactamases in multiple Escherichia coli clones isolated in Tel Aviv, Israel. Antimicrob Agents Chemother. 2005 Nov;49(11):474550. PubMed PMID: 16251320
  • Seputiene V, Linkevicius M, Bogdaite A, Povilonis J, Planciuniene R,Giedraitiene A, Pavilonis A, Suziedeliene E. Molecular characterization ofextended-spectrum ß-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from hospitals in Lithuania. J Med Microbiol. 2010 Oct;59(Pt 10):1263-5. doi: 10.1099/jmm.0.021972-0. Epub 2010 Jun 24. PubMed PMID: 20576750
  • Miró E, Mirelis B, Navarro F, Rivera A, Mesa RJ, Roig MC, Gómez L, Coll P.Surveillance of extended-spectrum beta-lactamases from clinical samples and faecal carriers in Barcelona, Spain. J Antimicrob Chemother. 2005Dec;56(6):1152-5. Epub 2005 Oct 21. PubMed PMID: 16244084
  • Poirel L, Potron A, De La Cuesta C, Cleary T, Nordmann P, Munoz-Price LS. Wild coastline birds as reservoirs of broad-spectrum-ß-lactamase-producing Enterobacteriaceae in Miami Beach, Florida. Antimicrob Agents Chemother. 2012May;56(5):2756-8. doi: 10.1128/AAC.05982-11. Epub 2012 Feb 6. PubMed PMID:22314536
  • Hächler H, Kotsakis SD, Tzouvelekis LS, Geser N, Lehner A, Miriagou V, StephanR. Characterisation of CTX-M-117, a Pro174Gln variant of CTX-M-15extended-spectrum ß-lactamase, from a bovine Escherichia coli isolate. Int JAntimicrob Agents. 2013 Jan;41(1):94-5.doi: 10.1016/j.ijantimicag.2012.09.011.Epub 2012 Nov 3. PubMed PMID: 23127481
  • Luo Y, Cui S, Li J, Yang J, Lin L, Hu C, Jin S, Ye L, Zhao Q, Ma Y.Characterization of Escherichia coli isolates from healthy food handlers inhospital. Microb Drug Resist. 2011 Sep;17(3):443-8. doi: 10.1089/mdr.2011.0032.Epub 2011 May 25. PubMed PMID: 21612511
  • Galani I, Souli M, Chryssouli Z, Giamarellou H. Detection of CTX-M-15 andCTX-M-33, a novel variant of CTX-M-15, in clinical Escherichia coli isolates inGreece. Int J Antimicrob Agents. 2007 May;29(5):598-600. Epub 2007 Jan 17. PubMedPMID: 17234386
  • Power P, Galleni M, Di Conza J, Ayala JA, Gutkind G. Description of In116, thefirst blaCTX-M-2-containing complex class 1 integron found in Morganella morganiiisolates from Buenos Aires, Argentina. J Antimicrob Chemother. 2005Apr;55(4):461-5. Epub 2005 Mar 2. PubMed PMID: 15743901
  • Heffernan HM, Woodhouse RE, Pope CE, Blackmore TK. Prevalence and types of extended-spectrum beta-lactamases among urinary Escherichia coli and Klebsiellaspp. in New Zealand. Int J Antimicrob Agents. 2009 Dec;34(6):544-9. doi:10.1016/j.ijantimicag.2009.07.014. Epub 2009 Sep 11. PubMed PMID: 19748232
  • Ranjbar R, Giammanco GM, Aleo A, Plano MR, Naghoni A, Owlia P, Mammina C.Characterization of the first extended-spectrum beta-lactamase-producing non typhoidal Salmonella strains isolated in Tehran, Iran. Foodborne Pathog Dis.2010 Jan;7(1):91-5. doi: 10.1089/fpd.2009.0382. PubMed PMID: 19785534
  • Cheng J, Wang Q, Chen Y, Ye Y, Li H, Li X, Li JB. Phenotypic and molecular characterization of a novel beta-lactamase carried by Klebsiella pneumoniae,CTX-M-72, derived from CTX-M-3. J Gen Appl Microbiol. 2009 Jun;55(3):207-16.PubMed PMID: 19590148
  • Bae IK, Lee BH, Hwang HY, Jeong SH, Hong SG, Chang CL, Kwak HS, Kim HJ, YounH. A novel ceftazidime-hydrolysing extended-spectrum beta-lactamase, CTX-M-54,with a single amino acid substitution at position 167 in the omega loop. J Antimicrob Chemother. 2006 Aug;58(2):315-9. Epub 2006 Jun 17. PubMed PMID:16785225
  • Cheng J, Gao W, Yin J, Sun Z, Ye Y, Gao YF, Li X, Li JB. Phenotypic and molecular characterization of two novel CTX-M enzymes carried by Klebsiellapneumoniae. Mol Biol Rep. 2010 Mar;37(3):1261-7. doi: 10.1007/s11033-009-9499-1. Epub 2009 Mar 18. PubMed PMID: 19294528
  • Oliver A, Coque TM, Alonso D, Valverde A, Baquero F, Cantón R. CTX-M-10 linked to a phage-related element is widely disseminated among Enterobacteriaceae in a Spanish hospital. Antimicrob Agents Chemother. 2005 Apr;49(4):1567-71. PubMedPMID: 15793141; PubMed Central PMCID
  • Yu Y, Ji S, Chen Y, Zhou W, Wei Z, Li L, Ma Y. Resistance of strains producing extended-spectrum beta-lactamases and genotype distribution in China. J Infect.2007 Jan;54(1):53-7. Epub 2006 Mar 13. PubMed PMID: 16533535
  • Schneider I, Queenan AM, Markovska R, Markova B, Keuleyan E, Bauernfeind A.New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with aGly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.Antimicrob Agents Chemother. 2009 Oct;53(10):4518-21. doi: 10.1128/AAC.00461-09. Epub 2009 Jul 20. PubMed PMID: 19620330
  • Bourouis A, Dubois V, Coulange L, André C, Bejhadj C, Ben Moussa M, Quentin C,Belhadj O. First report of CTX-M-9 in a clinical isolate of Enterobacter cloacae in a Tunisian hospital. Pathol Biol (Paris). 2011 Aug;59(4):187-91. doi:10.1016/j.patbio.2009.03.008. Epub 2009 May 28. PubMed PMID: 19481370
  • Bhattacharya D, Purushottaman SA, Bhattacharjee H, Thamizhmani R, Sudharama SD, Manimunda SP, Bharadwaj AP, Singhania M, Roy S. Rapid emergence of third-generation cephalosporin resistance in Shigella sp. isolated in Andaman and Nicobar Islands, India. Microb Drug Resist. 2011 Jun;17(2):329-32. doi:10.1089/mdr.2010.0084. Epub 2011 Feb 25. PubMed PMID: 21352076
  • Navon-Venezia S, Chmelnitsky I, Leavitt A, Carmeli Y. Dissemination of theCTX-M-25 family beta-lactamases among Klebsiella pneumoniae, Escherichia coli andEnterobacter cloacae and identification of the novel enzyme CTX-M-41 in Proteusmirabilis in Israel. J Antimicrob Chemother. 2008 Aug;62(2):289-95. doi:10.1093/jac/dkn182. Epub 2008 May 16. PubMed PMID: 18487232
  • Wu JJ, Chen HM, Ko WC, Wu HM, Tsai SH, Yan JJ. Prevalence of extended-spectrumbeta-lactamases in Proteus mirabilis in a Taiwanese university hospital, 1999 to 2005: identification of a novel CTX-M enzyme (CTX-M-66). Diagn Microbiol InfectDis. 2008 Feb;60(2):169-75. Epub 2007 Oct 29. PubMed PMID: 17913434
  • Fursova N, Pryamchuk S, Kruglov A, Abaev I, Pecherskikh E, Kartsev N, Svetoch E, Dyatlov I. The novel CTX-M-116 ß-lactamase gene discovered in Proteusmirabilis is composed of parts of the CTX-M-22 and CTX-M-23 genes. AntimicrobAgents Chemother. 2013 Mar;57(3):1552-5. doi: 10.1128/AAC.01471-12. Epub 2013 Jan14. PubMed PMID: 23318795
  • Soler Bistué AJ, Martín FA, Petroni A, Faccone D, Galas M, Tolmasky ME,Zorreguieta A. Vibrio cholerae InV117, a class 1 integron harboring aac(6')-Iband blaCTX-M-2, is linked to transposition genes. Antimicrob Agents Chemother.2006 May;50(5):1903-7. PubMed PMID: 16641475
  • Nagano Y, Nagano N, Wachino J, Ishikawa K, Arakawa Y. Novel chimericbeta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins,including ceftazidime. Antimicrob Agents Chemother. 2009 Jan;53(1):69-74. doi:10.1128/AAC.00227-08. Epub 2008 Oct 27. PubMed PMID: 18955524
  • Bonnet R, Sampaio JL, Labia R, De Champs C, Sirot D, Chanal C, Sirot J. Anovel CTX-M beta-lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceaeisolated in Brazil. Antimicrob Agents Chemother. 2000 Jul;44(7):1936-42. PubMedPMID: 10858358
  • Doublet B, Granier SA, Robin F, Bonnet R, Fabre L, Brisabois A, Cloeckaert A, Weill FX. Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhamptonand Senftenberg. Antimicrob Agents Chemother. 2009 May;53(5):1944-51. doi:10.1128/AAC.01581-08. Epub 2009 Mar 9. PubMed PMID: 19273683
  • Hopkins KL, Threlfall EJ, Karisik E, Wardle JK. Identification of novel plasmid-mediated extended-spectrum beta-lactamase CTX-M-57 in Salmonella entericaserovar Typhimurium. Int J Antimicrob Agents. 2008 Jan;31(1):85-6. Epub 2007 Nov 28. PubMed PMID: 18054206
  • Saladin M, Cao VT, Lambert T, Donay JL, Herrmann JL, Ould-Hocine Z, Verdet C, Delisle F, Philippon A, Arlet G. Diversity of CTX-M beta-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals. FEMS Microbiol Lett. 2002 Apr 9;209(2):161-8.PubMed PMID: 12007800
  • Govinden U, Mocktar C, Moodley P, Sturm AW, Essack SY. CTX-M-37 in Salmonella enterica serotype Isangi from Durban, South Africa. Int J Antimicrob Agents. 2006 Oct;28(4):288-91. Epub 2006 Sep 1.PubMed PMID: 16949257
  • Stepanova MN, Pimkin M, Nikulin AA, Kozyreva VK, Agapova ED, Edelstein MV. Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. Antimicrob Agents Chemother. 2008 Apr;52(4):1297-301. doi: 10.1128/AAC.01060-07. Epub 2008 Jan 22.PubMed PMID: 18212109
  • Celenza G, Pellegrini C, Caccamo M, Segatore B, Amicosante G, Perilli M. Spread of bla(CTX-M-type) and bla(PER-2) beta-lactamase genes in clinical isolates from Bolivian hospitals. J Antimicrob Chemother. 2006 May;57(5):975-8. Epub 2006 Mar 1.PubMed PMID: 16510850
  • de Oliveira Garcia D, Doi Y, Szabo D, Adams-Haduch JM, Vaz TM, Leite D, Padoveze MC, Freire MP, Silveira FP, Paterson DL. Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. Antimicrob Agents Chemother. 2008 May;52(5):1790-3. doi: 10.1128/AAC.01440-07.PubMed PMID: 18347108
  • Brasme L, Nordmann P, Fidel F, Lartigue MF, Bajolet O, Poirel L, Forte D, Vernet-Garnier V, Madoux J, Reveil JC, Alba-Sauviat C, Baudinat I, Bineau P, Bouquigny-Saison C, Eloy C, Lafaurie C, Siméon D, Verquin JP, Noël F, Strady C, De Champs C. Incidence of class A extended-spectrum beta-lactamases in Champagne-Ardenne (France): a 1 year prospective study. J Antimicrob Chemother. 2007 Nov;60(5):956-64. Epub 2007 Sep 5. Erratum in: J Antimicrob Chemother.PubMed PMID: 17804424
  • Wu JJ, Chen HM, Ko WC, Wu HM, Tsai SH, Yan JJ. Prevalence of extended-spectrum beta-lactamases in Proteus mirabilis in a Taiwanese university hospital, 1999 to 2005: identification of a novel CTX-M enzyme (CTX-M-66). Diagn Microbiol Infect Dis. 2008 Feb;60(2):169-75.PubMed PMID: 1791343
  • Schneider I, Queenan AM, Markovska R, Markova B, Keuleyan E, Bauernfeind A. New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria. Antimicrob Agents Chemother. 2009 Oct;53(10):4518-21. doi: 10.1128/AAC.00461-09. Epub 2009 Jul 20.PubMed PMID: 19620330
  • Rodríguez MM, Power P, Sader H, Galleni M, Gutkind G. Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. Antimicrob Agents Chemother. 2010 Jul;54(7):3070-1. doi: 10.1128/AAC.01615-09. Epub 2010 Apr 26.PubMed PMID: 19273683
  • He D, Partridge SR, Shen J, Zeng Z, Liu L, Rao L, Lv L, Liu JH. CTX-M-123, a novel hybrid of the CTX-M-1 and CTX-M-9 Group ?-lactamases recovered from Escherichia coli isolates in China. Antimicrob Agents Chemother. 2013 Aug;57(8):4068-71. doi: 10.1128/AAC.00541-13. Epub 2013 Jun 10.PubMed PMID: 23752509
  • Tian GB, Huang YM, Fang ZL, Qing Y, Zhang XF, Huang X. CTX-M-137, a hybrid of CTX-M-14-like and CTX-M-15-like ?-lactamases identified in an Escherichia coli clinical isolate. J Antimicrob Chemother. 2014 Aug;69(8):2081-5. doi: 10.1093/jac/dku126. Epub 2014 Apr 28. PubMed PMID: 24777903