Family: FOX
Class: C
Number of Variants: 10
Number of Proteins: 12
Number of Structures: 0
Taxonomic Lineage: Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae

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Variants Organism Uniprot ID PDB ID Hydrolytic profile Embl ID Genbank ID
FOX-1
Klebsiella pneumoniae Q48437 NA NA X77455 X77455.1
FOX-2 Escherichia coli O52988 NA Cephamycins Y10282 Y10282.1
Aeromonas caviae K9N0B7 NA Cephamycins JX849668 JX849668.1
FOX-3 Klebsiella oxytoca P94856 NA NA Y11068 Y11068.1
FOX-4 Escherichia coli Q9L387 NA NA AJ277535 AJ277535.1
FOX-5 Escherichia coli A0ESI2 NA NA DQ484079 DQ484079.1
FOX-6 Klebsiella pneumoniae Q9F4K3 NA NA AY007369 AY007369.1
FOX-7 Klebsiella pneumoniae Q53IN1 NA NA AJ703795 AJ703795.1
Klebsiella pneumoniae Q53IN0 NA NA AJ703796 AJ703796.1
FOX-8 Escherichia coliE2IKQ7 NA NA HM565917 HM565917.1
FOX-9 Klebsiella pneumoniae G1CS20 NA NA JF896803 JF896803.1
FOX-10 Klebsiella pneumoniae R4IWH1 NA NA JX049131 JX049131.1
References
  • Gonzalez Leiza M, Perez-Diaz JC, Ayala J, Casellas JM, Martinez-Beltran J,Bush K, Baquero F. Gene sequence and biochemical characterization of FOX-1 from Klebsiella pneumoniae, a new AmpC-type plasmid-mediated beta-lactamase with two molecular variants. Antimicrob Agents Chemother. 1994 Sep;38(9):2150-7.PubMed PMID: 7811034
  • Bauernfeind A, Wagner S, Jungwirth R, Schneider I, Meyer D. A novel class C beta-lactamase (FOX-2) in Escherichia coli conferring resistance to cephamycins. Antimicrob Agents Chemother. 1997 Sep;41(9):2041-6.PubMed PMID: 9303413
  • Marchese A, Arlet G, Schito GC, Lagrange PH, Philippon A. Characterization of FOX-3, an AmpC-type plasmid-mediated beta-lactamase from an Italian isolate of Klebsiella oxytoca. Antimicrob Agents Chemother. 1998 Feb;42(2):464-7. PubMed PMID: 9527810
  • Bou G, Oliver A, Ojeda M, Monzón C, Martínez-Beltrán J. Molecular characterization of FOX-4, a new AmpC-type plasmid-mediated beta-lactamase from an Escherichia coli strain isolated in Spain. Antimicrob Agents Chemother. 2000 Sep;44(9):2549-53.PubMed PMID: 10952615
  • Queenan AM, Jenkins S, Bush K. Cloning and biochemical characterization of FOX-5, an AmpC-type plasmid-encoded beta-lactamase from a New York City Klebsiella pneumoniae clinical isolate. Antimicrob Agents Chemother. 2001Nov;45(11):3189-94.PubMed PMID: 11600376