Family: GOB
Class: B
Sub Class: B3
Number of Variants: 10
Number of Proteins: 12
Number of Structures: 0
Taxonomic Lineage: Bacteria > Bacteroidetes > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Elizabethkingia

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Variants Organism Uniprot ID PDB ID Hydrolytic profile Embl ID Genbank ID
GOB-1
Flavobacterium meningosepticum A4GRB7 NA Carbapenem EF394442 ABO21417.1
Flavobacterium meningosepticum Q9RB00 NA Carbapenem AF090141 AF090141.1
Elizabethkingia meningoseptica Q9K316 NA Carbapenem AF189294 AF189294.1
GOB-2 Elizabethkingia meningoseptica Q9KJB2 NA Carbapenem AF189296 AF189296.1
GOB-3 Elizabethkingia meningoseptica Q9KJB5 NA Carbapenem AF189291 AF189291.1
GOB-4 Elizabethkingia meningoseptica Q9KJB3 NA Carbapenem AF189293 AF189293.1
GOB-5 Elizabethkingia meningoseptica Q9KJB6 NA Carbapenem AF189290 AF189290.1
GOB-6 Elizabethkingia meningoseptica Q9KJB4 NA Carbapenem AF189292 AF189292.1
GOB-7 Elizabethkingia meningoseptica Q9KJB1 NA Carbapenem AF189297 AF189297.1
GOB-16 Flavobacterium meningosepticum Q5EEU5 NA Carbapenem AY899331 AY899331.1
GOB-17 Flavobacterium meningosepticum Q5EEU4 NA Carbapenem AY899332 AY899332.1
GOB-18 Flavobacterium meningosepticum Q4JRB6 NA Carbapenem DQ004496 AAY53478.1
References
  • Yum JH, Lee EY, Hur SH, Jeong SH, Lee H, Yong D, Chong Y, Lee EW, Nordmann P,Lee K. Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea. J Microbiol. 2010Jun;48(3):358-64. doi: 10.1007/s12275-010-9308-5. Epub 2010 Jun 23. PubMed PMID: 20571954
  • Morán-Barrio J, González JM, Lisa MN, Costello AL, Peraro MD, Carloni P,Bennett B, Tierney DL, Limansky AS, Viale AM, Vila AJ. The metallo-beta-lactamase GOB is a mono-Zn(II) enzyme with a novel active site. J Biol Chem. 2007 Jun22;282(25):18286-93. Epub 2007 Apr 2. PubMed PMID: 17403673
  • Bellais S, Aubert D, Naas T, Nordmann P. Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum. Antimicrob Agents Chemother. 2000Jul;44(7):1878-86. PubMed PMID: 10858348