Family: IND
Class: B
Sub Class: B1
Number of Variants: 14
Number of Proteins: 18
Number of Structures: 1
Taxonomic Lineage: Bacteria > Bacteroidetes > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Chryseobacterium

  Alignment     Variability Plot     Phylogenetic Tree     Mutational Profile     Fingerprint     Sequences  

Variants Organism Uniprot ID PDB ID Hydrolytic profile Embl ID Genbank ID
IND-1 Chryseobacterium indologenes A4GRB2 3L6N Carbapenem EF394437 EF394437.1
Chryseobacterium indologenes A4GRB1 NA Carbapenem EF394436 EF394436.1
IND-2 Chryseobacterium indologenes Q9ETN2 NA Carbapenem EF672681 EF672681.1
Chryseobacterium indologenes A4GRB4 NA Carbapenem EF394439 EF394439.1
Chryseobacterium indologenes A4GRB3 NA Carbapenem EF394438 EF394438.1
Chryseobacterium indologenes Q9F923 NA Carbapenem AF219128 AF219128.1
IND-3 Chryseobacterium indologenes Q9EU43 NA Carbapenem AF219133 AF219133.2
IND-4 Chryseobacterium indologenes Q9F921 NA Carbapenem AF219135 AF219135.2
IND-6 Chryseobacterium indologenes Q08I33 NA Carbapenem AM087455 AM087455.1
IND-7 Chryseobacterium indologenes D2K7N8 NA Carbapenem GU186043 GU186043.1
IND-8 Chryseobacterium indologenes D2K7N9 NA Carbapenem GU186044 GU186044.1
IND-9 Chryseobacterium indologenes D2K7P0 NA Carbapenem GU186045 GU186045.1
IND-10 Chryseobacterium indologenes D2KCJ9 NA Carbapenem GU206353 GU206353.1
IND-11 Chryseobacterium indologenes E0A2V6 NA Carbapenem HM245379 HM245379.1
IND-12 Chryseobacterium indologenes E0A2V7 NA Carbapenem HM245380 HM245380.1
IND-13 Chryseobacterium indologenes Q9F922 NA Carbapenem HM245381 HM245381.1
IND-14 Chryseobacterium indologenes E2GLP7 NA Carbapenem HM367709 HM367709.1
IND-15 Chryseobacterium indologenes D9N4D1 NA Carbapenem AB563173 AB563173.1
References
  • Bellais S, Poirel L, Leotard S, Naas T, Nordmann P. Genetic diversity of carbapenem-hydrolyzing metallo-beta-lactamases from Chryseobacterium(Flavobacterium) indologenes. Antimicrob Agents Chemother. 2000Nov;44(11):3028-34.PubMed PMID: 11036018
  • Yamaguchi Y, Takashio N, Wachino J, Yamagata Y, Arakawa Y, Matsuda K, KurosakiH. Structure of metallo-beta-lactamase IND-7 from a Chryseobacterium indologenesclinical isolate at 1.65-A resolution. J Biochem. 2010 Jun;147(6):905-15. doi:10.1093/jb/mvq029. Epub 2010 Mar 19. PubMed PMID: 20305272
  • Lin XH, Xu YH, Cheng J, Li T, Wang ZX. Heterogeneity of bla(IND)metallo-beta-lactamase-producing Chryseobacterium indologenes isolates detectedin Hefei, China. Int J Antimicrob Agents. 2008 Nov;32(5):398-400. doi:10.1016/j.ijantimicag.2008.04.028. Epub 2008 Aug 15.PubMed PMID: 18707850
  • Tullius MV, Munson RS Jr, Wang J, Gibson BW. Purification, cloning, and expression of a cytidine 5'-monophosphate N-acetylneuraminic acid synthetase fromHaemophilus ducreyi. J Biol Chem. 1996 Jun 28;271(26):15373-80. PubMed PMID:8663048
  • Bozue JA, Tullius MV, Wang J, Gibson BW, Munson RS Jr. Haemophilus ducreyiproduces a novel sialyltransferase. Identification of the sialyltransferase gene and construction of mutants deficient in the production of the sialicacid-containing glycoform of the lipooligosaccharide. J Biol Chem. 1999 Feb12;274(7):4106-14.PubMed PMID: 9933604.
  • Zeba B, De Luca F, Dubus A, Delmarcelle M, Simporé J, Nacoulma OG, Rossolini GM, Frère JM, Docquier JD. IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. Antimicrob Agents Chemother. 2009 Oct;53(10):4320-6. doi: 10.1128/AAC.01607-08. Epub 2009 Aug 3.PubMed PMID:19651915
  • Perilli M, Caporale B, Celenza G, Pellegrini C, Docquier JD, Mezzatesta M, Rossolini GM, Stefani S, Amicosante G. Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes. Antimicrob Agents Chemother. 2007 Aug;51(8):2988-90. Epub 2007 Apr 30.PubMed PMID:17470648